Studies of interest
Mesenchymal cells are stem cells in the mesenchyme of the embryo. They are capable of differentiating into many cell types.
They are present in very small amounts in adults.
The term “mesenchymal stem cells” was coined by Arnold Caplan in 1991. These are original mesodermal stem cells present in various tissues of the adult body such as the bone marrow or adipose tissue. They are also present in the umbilical cord.
Mesenchymal stem cells can differentiate into different specialized cells found in skeletal tissues: bone cells (osteoblasts), cartilage cells (chondrocytes) and fat cells (adipocytes).
Preliminary investigations have suggested that mesenchymal stem cells can also differentiate into many cell types that are not part of the skeletal tissues, such as nerve cells, heart muscle cells, liver cells and endothelial cells, which form the inner layer of blood vessels.
Notice: Them use of embryonic mesenchymal stem cells has not yet been approved by Health Canada.
- Metabolism as an early predictor of DPSCs aging
- LncRNA H19 promotes the committed differentiation of stem cells from apical papilla via miR-141/SPAG9 pathway
- KIAA1199 is a secreted molecule that enhances osteoblastic stem cell migration and recruitment
- Hypoxia preconditioning promotes bone marrow mesenchymal stem cells survival by inducing HIF-1α in injured neuronal cells derived exosomes culture system
- Soluble TRAIL Armed Human MSC As Gene Therapy For Pancreatic Cancer
- Molecular signature of human bone marrow-derived mesenchymal stromal cell subsets
- Haematopoietic stem cell activity and interactions with the niche
- Therapeutic potential of hepatocyte-like-cells converted from stem cells from human exfoliated deciduous teeth in fulminant Wilson’s disease
- High doses of synthetic antioxidants induce premature senescence in cultivated mesenchymal stem cells
- Volume expansion and TRPV4 activation regulate stem cell fate in three-dimensional microenvironments
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