Studies of interest
Mesenchymal cells are stem cells in the mesenchyme of the embryo. They are capable of differentiating into many cell types.
They are present in very small amounts in adults.
The term “mesenchymal stem cells” was coined by Arnold Caplan in 1991. These are original mesodermal stem cells present in various tissues of the adult body such as the bone marrow or adipose tissue. They are also present in the umbilical cord.
Mesenchymal stem cells can differentiate into different specialized cells found in skeletal tissues: bone cells (osteoblasts), cartilage cells (chondrocytes) and fat cells (adipocytes).
Preliminary investigations have suggested that mesenchymal stem cells can also differentiate into many cell types that are not part of the skeletal tissues, such as nerve cells, heart muscle cells, liver cells and endothelial cells, which form the inner layer of blood vessels.
Notice: Them use of embryonic mesenchymal stem cells has not yet been approved by Health Canada.
- Proteomic analysis of human mesenchymal stromal cell secretomes: a systematic comparison of the angiogenic potential
- Metabolites can regulate stem cell behavior through the STAT3/AKT pathway in a similar trend to that under hypoxic conditions
- Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp
- Differentiating SGBS adipocytes respond to PPARγ stimulation, irisin and BMP7 by functional browning and beige characteristics
- Significance of the Tks4 scaffold protein in bone tissue homeostasis
- Magic realism: a Latin American paradigm for stem cell research & development?
- Optimization of the adipose-derived mesenchymal stem cell delivery time for radiation-induced lung fibrosis treatment in rats
- Effect of cell culture density on dental pulp-derived mesenchymal stem cells with reference to osteogenic differentiation
- Harnessing the mesenchymal stem cell secretome for regenerative urology
- On making bones or fat
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